Name: Cytokeratin 8 antibody clone EP17
Description and aplications: Cytokeratin 8 (CK8) is an intermediate filament protein produced early in embryogenesis. It is the only type-II CK occurring in many simple epithelial in respiratory, gastrointestinal, male and female reproductive tract and thyroid. CK8 is often co-expressed with Cytokeratin 18. CK8/18 is the major keratin pair in simple-type epithelia, as found in the liver, pancreas, and intestine. CK8 antibody is used to detect adenocarcinomas with simple epithelium origin. The difference in staining pattern is useful to distinguish duct (peripheral staining) from lobular (perinuclear staining) breast carcinoma
Composition: anti-human cytokeratin 8 rabbit monoclonal antibody purified from ascites. Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide
Immunogen: A synthetic peptide corresponding on the C-terminus
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