آنتی بادی مونوکلونال فلوسیتومتری CD2-FITC، کلون RPA-2.10

Name: Flow Cytometry Antibody CD2-FITC, Clone RPA-2.10

• Antibody CD2-FITC is a monoclonal antibody (mAb) labelled with fluorescein isothiocyanate (FITC) designed for use as a direct immunofluorescence reagent in the identification and enumeration of cells which express the CD2 antigen by flow cytometry (FC). CD2 can be considered a pan-T cell antigen, as it is expressed on the surface of all normal Tlymphocytes. This reagent must be used by flow cytometry qualified personal.

SUMMARY AND EXPLANATION

 The CYT-2F7 mAb recognizes the 50kDa lymphocyte surface antigen expressed on all peripheral blood T lymphocytes, the majority of thymocytes and malignant cells of T cell origin, including T ALL cells. CD2 is a useful marker in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and posthymic lymphomas and leukemias. In some neoplastic T-cell populations e.g. in peripheral T cell lymphomas, CD2 may be aberrantly deleted.

 REAGENT COMPOSITION

Purified monoclonal CD2 antibody conjugated with fluorescein isothiocyanate (FITC), supplied in phosphate buffered saline with 0,09% sodium azide.

• Clone: RPA-2.10
• Isotype: IgG1
• Purification: Affinity chromatography
• Amount per 1 mL vial: 200 tests (5 µL mAb to 106 cells)
• Reagents are not considered sterile.