Name: SOX-2 Antibody (Clone SP76)
Description and applications: Sex determining region Y-box 2 (SOX-2) is a stem cell marker and a transcription factor expressed in basal cells of the prostate, myoepithelial cells of the breast, squamous epithelium, and fetal neural cells. Recent studies show that SOX-2 is highly expressed in some human cancers such as prostate, lung, breast, and ovarian cancers. SOX2 is a sensitive marker of
embryonal carcinoma.
Composition: Anti-human SOX-2 rabbit monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen: Synthetic peptide corresponding to Nterminus of human SOX-2 protein.