Clone | QR068 |
---|---|
REF | C-C026 |
Dilution | 1:100 – 1:200 |
Immunogen | Synthetic peptide of human CD8 |
Isotype | IgG |
Species of origin | Rabbit |
CD8 is a transmembrane glycoprotein and co-receptor that functions together with T cell receptor (TCR) in adaptive immune response. CD8 is mainly expressed on cytotoxic T cells as well as natural killer cells, cortical thymocytes and dendritic cells. Furthermore, CD8 is expressed in T cell LGL leukemia and together with CD4 in some T lymphoblastic lymphoma.CD8 can be detected in colorectal carcinoma and ovarian, renal, hepatocellular and esophageal tumors.