| Clone | QR045 |
|---|---|
| REF | C-C016 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human CDX2 |
| Isotype | IgG |
| Species of origin | Rabbit |
CDX2, also known as caudal-related homeodomain protein 2, is a transcription factor expressed in intestine, but not in stomach and esophagus. CDX2 may play an important role in proliferation and differentiation of intestinal epithelial cells. Antibody CDX2 may be useful in detection of colorectal carcinoma with reduced or absent expression. On the other hand CDX2 is expressed in gastric intestinal metaplasia, dysplasia and carcinoma, as well as in acute myeloid leukemia.
