Clone | QR026 |
---|---|
REF | C-D001 |
Dilution | 1:100 – 1:200 |
Immunogen | Synthetic peptide of human Desmin |
Isotype | IgG |
Species of origin | Rabbit |
Desmin is a muscle-specific intermediate filament protein type III and is found in the dense bodies of smooth muscle cells and in the Z-disk of striated muscles. Desmin connects the contractile apparatus to the subsarcolemmal cytoskeleton and organelles like nuclei. It also forms a scaffold around the myofibrillar Z-disk. It is useful in the detection of tumors with myoid origin and to differentiate mesothelioma from carcinoma.