| Clone | QR023 |
|---|---|
| REF | C-S002 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human SATB2 |
| Isotype | IgG |
| Species of origin | Rabbit |
SATB2 is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. It is highly expressed in adult and fetal brain, and weak expressed in liver, kidney, and spinal cord as well as some brain regions. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.
