| Clone | QR101 |
|---|---|
| REF | C-M011 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human MPO |
| Isotype | IgG |
| Species of origin | Rabbit |
Myeloperoxidase is a peroxidase enzyme. This antibody detects granulocytes and monocytes in blood and precursors of granulocytes in the bone marrow. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas. MPO is useful in differentiating between myeloid and lymphoid leukemias.
