آنتی بادی CD21 کلون 2G9 برند Patho Sage

Specification:

CD21, also knows as CR2, C3d receptor and EBV receptor, is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B cell intogeny, cd 21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as a receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNaplha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Presentation:

Anti-CD21 is a mouse monoclonal antibody from supernatant diluted in phosphate buffered saline, pH 7.4, with protein base, and preserved with sodium azide